产品货号：
Z29521
中文名称：
UBA1抗体
英文名称：
Anti-UBA1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UBA1 Antibody |
| 指标别名 | A1S9;A1S9T;A1ST;AMCX1;GXP1;Protein A1S9;SMAX2;UBA1;UBA1A;UBE1;UBE1X;Ubiquitin activating enzyme E1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | UBA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human UBA1 (102-139aa HDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELN),different from the related mouse and rat sequences by one amino acid. |
| 实际分子量 | 118KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Ubiquitin-like modifier activating enzyme 1 (UBA1) is an enzyme which in humans is encoded by the UBA1 gene.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation,or ubiquitination,to mark cellular proteins for degradation.Specifically,UBA1 catalyzes the ATP-dependent adenylation of ubiquitin (Ub),thereby forming a thioester bond between the two.It also continues to participate in subsequent steps of ubiquination as a Ub carrier.UBA1 is one of only two human ubiquitin-activating enzymes (E1),the other being UBA6,and thus is largely responsible for protein ubiquitination in humans.Through its central role in ubiquitination,UBA1 has been linked to cell cycle regulation,endocytosis,signal transduction,apoptosis,DNA damage repair,and transcriptional regulation.Additionally,UBE1 helps regulate the NEDD8 pathway,thus implicating it in protein folding,as well as mitigating the depletion of ubiquitin levels during stress. |
| Uniprot ID | P22314 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | ubiquitin like modifier activating enzyme 1 |
| 蛋白名全称 | Ubiquitin-like modifier-activating enzyme 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：UBA1抗体，UBA1多抗，Anti-UBA1 Antibody